University of the Basque Country - Summer course:
Attention Deficit/Hyperactivity Disorder (ADHD), a neurodevelopmental psychiatric disorder:
clinical impact, neurobiological mechanisms and comorbidity

ADHD is a developmental disorder associated with cognitive, emotional, and behavioral deficits. Its main symptoms are impulsivity, hyperactivity, and inattention (American Psychiatric Association, 2000). It is one of the most common psychiatric pathologies in children with an estimated prevalence of 8-12% worldwide, and symptoms persist until adulthood in up to two-third of cases. Numerous studies have demonstrated the interactions between ADHD and other disorders that may aggravate the symptoms or the long-term outcome of the disease. Indeed, associations have been described with impaired perceptual function, and particularly pain.

The course activities will follow the categories

  1. Master classes. The current knowledge on the disease, treatments and sensory comorbidity (i.e. alteration of pain perception) will be presented through  The clinical impact of the disease will be explained. The use of animal models to unravel underlying neurobiological mechanisms in a translational perspective will be assessed and neuroinflammatory processes will be highlighted.
  2. Mini-challenges. Participants will team up to think about the interactions between comorbid disorders and their societal outcomes.  with the objective of (i) raise hypothesis on comorbidity mechanisms, treatment-induced side effects, and (ii) elaborate scientific strategies to test their hypothesis.
  3. Round tables. attendees and course organizers, will participate  to discuss (i) the societal representation and acceptance of, or myths associated to, the disease, (ii) the consequences of comorbidity on well-being and therapeutical strategies, (iii) the possible increased prevalence of ADHD, and (iv) the translation of basic research into clinical applications through a bench to bedside approach.

Aims of the course

  • Understanding the ADHD disease: symptoms, neurobiological mechanisms, treatment opportunities.
  • Understanding interactions with comorbid disorders and their clinical consequences.
  • Reflecting on the burden associated to ADHD and its worsening due to comorbidities.
  • Developing a person-centered holistic view in a clinical context.

 

Competences

  • Raising scientific hypothesis
  • Elaborating scientific strategies to develop hypothesis-driven pre-clinical experiments or clinical studies
  • Proposing new actions for a public outreach strategy, thus limiting the propagation of distorted understanding by the lay public.
  • Improving teamwork capacity
  • Capability of synthesizing different visions to elaborate a final, common proposal

 

 

Supervisors

Marc Landry
Position: Professor
Institution: University of bordeaux
Language of the lecture: English

Country: France
City: Bordeaux

Nora Kerekes
Position: Professor
Institution: University West
Language of the lecture: English
Country: Sweden
City: Trollhättan

Ana Maria Sanchez Perez
Position: Professor
Institution: University Jaume I
Language of the lecture: English
Country: Spain
Province: Valencia
City: Castellon

Anticipated dates
July 2022

The venue
Gipuzkoa - Donostia/San Sebastian

Teaching methodology

Face-to-face + live online: Master class
Mini challenge
Round table

Course schedule

Course language: English

Day 1

08:45 - 09:00
Registration

09:00 - 09:15
Presentation by the Director of the activity

Lecturer: Marc Landry

09:15 - 10:00
General characteristics of ADHD: clinical symptoms, epidemiology, comorbidity.

Lecturer: Nora Kerekes

10:00 - 10:45
Animal models of ADHD : nature and validity

Lecturer: Marc Landry

10:45 - 11:15
Break

11:15 - 13:30
Mini-challenges aiming to raise hypothesis and determine experimental strategies to unravel the mechanisms of comorbidity: presentation, team activation, material delivery and reflection.

13:30 - 14:00
Discussion on the mini-challenges with the organizers - answering questions

14:00 - 15:30
Lunch break

15:30 - 16:45 
Mini team presentation.

16:45 - 17:00
Closing session

Lecturer: Ana Maria Sanchez Pere

Day 2

08:45 - 09:00
Registration

09:00 - 09:45
Mechanisms underpinning ADHD with a special emphasis on neuroinflammation 

Lecturer: Ana Maria Sanchez Pere

09:45 - 10:30
ADHD treamtents: pharmacological and non-pharmacological treatments 

Lecturer: Nora Kerekes

10:30 - 11:30
Round table

Societal and translational aspects

Lecturer: Marc Landry

Lecturer: Nora Kerekes

Lecturer: Ana Maria Sanchez Perez

11:30 - 12:00
Break

12:00 - 13:00
Conclusions of the round tables by the spokesperson of each table .

13:00 - 13:45
Sintesis 

13:45 - 14:00
Closing session 

Lecturer: Marc Landry